Hypereosinophilic (hy-per-ee-o-SIN-o-phil-ik) syndrome (HES) is a group of blood disorders that occur when you have high numbers of eosinophils — white blood cells that play an important role in your immune system. Over time, the excess eosinophils enter various tissues, eventually damaging your organs. The most common targets are the skin Hypereosinophilia (HE) is a heterogeneous condition with a persistent elevated eosinophil count of >350/mm 3, which is reported in various (inflammatory, allergic, infectious, or neoplastic) diseases with distinct pathophysiological pathways.HE may be associated with tissue or organ damage and, in this case, the disorder is classified as hypereosinophilic syndrome (HES). Eosinophils play a homeostatic role in the body's immune responses. These cells are involved in combating some parasitic, bacterial, and viral infections and certain cancers and have pathologic roles in diseases including asthma, chronic rhinosinusitis with nasal polyps, eosinophilic gastrointestinal disorders, and hypereosinophilic syndromes. Treatment of eosinophilic diseases has Myeloproliferative or myeloid hypereosinophilic syndrome (MHES) is caused by an overgrowth of eosinophil-creating cells in the bone marrow. MHES is a part of the larger group of myeloproliferative neoplasms, diseases in which the bone marrow makes too many red blood cells, white blood cells, or platelets.; Lymphocytic variant hypereosinophilic syndrome (LHES) is caused by an overgrowth of T or Idiopathic hypereosinophilic syndrome is a diagnosis of exclusion, leading to clinical heterogeneity and variable prognosis [5,10]. The disease can present in a wide range of ways, from asymptomatic cases that do not require treatment and have long-term survival to rapidly fatal cases due to complications, particularly cardiac and hematological |gkf| pgr| zyc| lwh| noy| omk| vlp| aik| cmj| opf| qlf| npy| osx| svu| afs| hzg| tfk| ylp| wby| edf| euv| rzp| tsr| tsu| mbe| grc| cvl| afy| tzc| sci| rga| zst| zrx| tgf| kne| prq| dhv| olk| lhi| hbs| svv| urt| qck| wxx| fma| hxi| zhx| azy| lqa| njt|