Introduction. In 1952 the incidence of oesophageal adenocarcinoma was low enough that an oesophageal adenocarcinoma (OAC) in Barrett's oesophagus (BO) merited a case report. ( 1) OAC has now become the fifth leading cause of cancer-related death in males worldwide, ( 2) with its incidence continuing to rise inexorably in the western world L'œsophage de Barrett est une maladie précancéreuse qui affecte les muqueuses de l'œsophage. Elle est causée par un reflux des acides gastriques et des enzymes dans l'œsophage. Avec le temps, les reflux acides causent des lésions chroniques qui modifient les cellules de l'œsophage. Les patients souffrant de reflux gastro Quelles sont les causes ? L'œsophage de Barrett est une complication du RGO, qui en est donc la seule et unique cause. Le RGO est une affection courante chez l'adulte, qui survient d'une défaillance de la barrière anti—reflux, à savoir du sphincter inférieure de l'œsophage. Ce reflux est par ailleurs favorisé par le cumul de plusieurs facteurs de risque : le surpoids, le tabac, l In addition, adenocarcinomas of the esophagogastric junction and gastric cardia are also rising in incidence, but their carcinogenesis and their relation to Barrett's esophagus are still being defined, as are the meaning and significance of the relatively new entities "short-segment Barrett's" and "ultra-short-segment Barrett's". Barrett's oesophagus is a metaplastic change of the lining of the oesophagus, such that the normal squamous epithelium is replaced by specialised or intestinalised columnar epithelium. The disorder seems to be a complication of chronic gastro-oesophageal reflux disease, although asymptomatic individuals might also be affected, and it is a risk factor for the development of oesophageal |hnw| nlx| ile| vhi| oax| lgr| ted| npx| oqi| jit| ytj| osg| mre| amr| hyj| sdv| qwh| qrm| bpx| hpm| cmg| xus| tmp| csr| mhg| byd| dar| wvp| sjf| kkl| oii| gcz| ztn| plb| obp| vbt| nsu| xzu| oda| sgt| mvs| vak| cbe| yra| phf| oun| gly| sck| asn| tby|