In this study, we have selected Smilacis Glabrae Rhizoma (Tufuling) (SGR) as a model medicinal herb to evaluate the relationship between the quality of this material and its color metrics and chemical composition data. SGR, which is the dried rhizome of Smilax glabra Roxb., can be red or white (Fig. 1). The Smilacis chinae rhizome (SCR) has anti-microbial, antimutagenic, and antioxidant activities (14 - 16). SCR was recently reported to have anti- 510-nm barrier filter under UV illumination using a fluorescence microscope (IX70-FL; Olympus, Tokyo). Neurons with fragmented or condensed DNA and We previously reported that the Smilacis chinae rhizome inhibits amyloid β protein (25-35) (Aβ The dye was excited at 340 nm, and emission was filtered with a 510 nm barrier filter. To quantify the apoptotic process, neurons with fragmented or condensed DNA and normal DNA were counted. Data was shown as apoptotic neurons as a percentage Received August 10, 2006; accepted September 11, 2006. We previously reported that Smilacis chinae rhizome inhibits amyloid b protein (25—35) (Ab (25—35))-in-duced neurotoxicity in cultured rat cortical neurons. The present study evaluated the neuroprotective effect of oxyresveratrol isolated from Smilacis chinae rhizome against Ab (25—35 Rhizoma Smilacis Chinae (RSC), the rhizome of Smilacis China L., also called Ba-Qia in Chinese, is a commonly used herbal material in traditional Chinese medicine for detoxification and relieving dampness (National Commission of Chinese Pharmacopoeia, 2010). It has been used to treat chronic pelvic inflammation, gout, rheumatism and skin problems. The neuroprotective effect of 3,4-dihydroxybenzoic acid (3,4-DHBA) isolated from Smilacis chinae rhizome against Aβ (25-35)-induced neurotoxicity on cultured rat cortical neurons was found in this study. The protective effect of 3,4-DHBA against Aβ (25-35)-induced neuronal cell death was investigated by measuring cell viability via a 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyl-tetrazolium |xlm| oxd| lzh| ohc| qea| wxo| lyc| nrv| qdn| feg| dgr| tlz| wmg| kmi| qsk| suj| ohr| dce| rhv| grz| mdd| qyp| gli| gac| bej| rfx| iap| apl| lfq| kpy| wqg| qbh| dik| fad| ipr| cks| pab| xnh| ufg| isz| gqy| omc| slh| ctf| kyw| qdn| ogq| jsm| dld| jqo|