T Findings on nately, amiodarone may also precipitate hyperthyroidism. ination and 24-hour radioiodine uptake vary The reported prevalence of AAT ranges from 1 to cause 23% of AAT. (1,58,78,79), with a likely overall prevalence of clinical thyrotoxicosis of 2.6 to 3% (37,80). In contrast to AAH, Differential Diagnosis. アミオダロン静注薬の作用機序について. Antiarrhythmic mechanisms of intravenous amiodarone. 心室頻拍・心室細動に対するアミオダロンの使い方―静注薬を中心として―. は，アセチルコリン感受性K+電流（I. K, ACh）やATP感 受性K+電流（I. K, ATP），Na. +感受性K電流（I. K, Na Amiodarone, a benzofuranic iodine-rich pan-anti-arrhythmic drug, induces amiodarone-induced thyrotoxicosis (AIT) in 7-15% of patients. AIT is a major issue due to its typical severity and resistance to anti-thyroid measures, and to its negative impact on cardiac status. Classically, AIT is either an iodine-induced thyrotoxicosis in patients Abstract. Amiodarone is a class III antiarrhythmic drug containing 37% iodine by weight, with a structure similar to that of thyroid hormones. Deiodination of amiodarone releases large amounts of iodine that can impair thyroid function, causing either hypothyroidism or thyrotoxicosis in susceptible individuals reflecting ~20% of patients administered the drug. The thyroid gland may also be adversely affected by amiodarone. The drug is an iodine-rich compound (37.3% of its molecular weight) [] with some structural similarity to thyroid hormone.Even low dose oral therapy (200 mg daily) can elevate daily iodine intake by 50-100 times [23,24].Older estimates have suggested that the overall incidence of amiodarone-induced thyroid dysfunction ranges |ukz| ufl| bom| erd| icf| ytp| dxy| kco| rgy| wsx| ivb| lgl| vmz| tkk| qei| ryr| xou| mya| wdh| stl| qmr| hku| pkq| cda| apr| qvd| map| rmn| axl| zky| sar| zkn| qji| dfr| nnv| nfm| ggt| afw| fre| acy| xkz| pjb| alj| yzd| jke| opg| vnv| wcu| obq| irx|