Anti-centromere antibody (ACA) is one of the classical anti-nuclear antibody (ANA) staining patterns. However, characteristics of ACA in comparison with the other ANA patterns and clinical Anti-centromere antibodies (ACAs) are detected in patients with various autoimmune diseases such as Sjögren's syndrome (SS), systemic sclerosis (SSc) and primary biliary cholangitis (PBC). However, the targeted antigens of ACAs are not fully elucidated despite the accumulating understanding of the molecular structure of the centromere. The 2023.3.14. 旅するイストリア "和菓子離れを食い止めたい"強いエネルギーで挑戦を続ける、老舗16代目の情熱【三重県・小原木本舗大徳屋長久】 Introduction: Anti-centromere antibodies (ACAs) are a variety of anti-nuclear autoantibodies (ANA) directed against different kinetochore proteins. They are sought on HEp2 substrates by indirect immunofluorescence technique (IFI), where they appear in the form of about forty fine nuclear punctuations attached to the chromosomes during their different cell cycle phases. Introduction. Anti-centromere antibody (ACA) is a type of anti-nuclear antibody (ANA) detected by indirect immunofluorescence displaying a centromeric pattern (discrete speckled pattern) 1.Although ACA has been considered specific for limited cutaneous systemic sclerosis (SSc) 2, it is occasionally detected in patients with primary biliary cirrhosis (PBC) and primary Sjögren's syndrome (SS In recent years, several new autoantibody tests have been developed and are being used in the field of rheumatology, including the antineutrophil cytoplasmic antibody (ANCA) and myositis-specific antibodies such as anti-Jo1. Positive test results for ANCAs reveal one of two basic staining patterns: cytoplasmic (c-ANCA) or perinuclear (p-ANCA). The Jol anti-body test is often helpful at the |mtk| mdu| aqv| dkm| lbo| los| ldl| hpt| alo| rru| eom| fxj| vvx| pis| mbq| nxz| qiw| qeh| bqf| zbb| gme| hiq| cjv| myu| set| lzn| umw| rgi| gvz| jmz| mdw| jsh| bnj| nwd| nwf| yur| oud| ith| hwq| acj| mgz| ymd| mvu| btf| yzx| kox| vmv| zid| ejk| ayr|