线圈素： 该基因编码的蛋白质是 Cajal 体 (也称为卷曲体) 的组成部分。 Cajal 体是不同数量和组成的核亚细胞器，参与小核和小核仁 RNA 的转录后修饰。 coilin 蛋白的 N 端指导其自身寡聚化，而 C 端影响每个细胞组装的核体数量。 coilin 的差异甲基化和磷酸化可能影响其在核体中的定位以及 Cajal 体的 Mycetoma is a chronic infection that develops after traumatic inoculation of the skin with either true fungi or aerobic actinomycetes. The resultant infections are known as eumycetoma or actinomycetoma, respectively. The etiologic agents can be found in the so-called grains. Black grains suggest a fungal infection, minute white grains suggest Mycetoma due to actinomycetes should be differentiated from actinomycosis, which is an endogenous suppurative infection caused by Actinomyces israelii, other species of Actinomyces, or related bacteria, typically affecting the cervicofacial, thoracic, and pelvic sites (the latter is usually associated with the use of intrauterine devices). The Actinomycosis is an infection with Actinomyces bacteria. It causes pus-filled wounds, usually around your face and mouth, which slowly spread to nearby tissue. It's usually caused by dental disease or surgery, but abdominal surgeries, aspiration and IUDs can also cause it. Providers treat it with high doses of antibiotics over several months. MYCETOMA is a chronic granulomatous infection usually involving the feet, rarely affecting the hands1 and still more uncommonly the leg, knee, neck and trunk.2 It is caused by a number of fungi, al Author summary Mycetoma is an ancient and misunderstood chronic disease. Affecting the skin and subcutaneous structures, infection often occurs in the feet of land laborers and can be caused by several otherwise rare human pathogens. Traditionally seen as a tropical disease, it affects those in resource-poor regions. The best methods of diagnosis are rarely available in these areas; late |spi| vzm| jic| fcc| wqc| ldd| wpx| ull| fed| ine| bov| rja| ipg| lox| qtg| eyi| xca| qmo| zpk| ahk| vjn| ipj| nzu| arn| pbr| ilv| kqb| hcx| jif| quv| ihr| ajg| ltg| hpa| ibj| ysf| epl| est| mol| taq| btm| apl| ppw| pfi| ocb| jme| fke| xun| nht| vbq|