Abstract. Hans Selye's single author short letter to Nature (1936, 138(3479):32) inspired a huge and still growing wave of medical research. His experiments with rats led to recognition of the "general adaptation syndrome", later renamed by Selye "stress response": the triad of enlarged adrenal glands, lymph node and thymic atrophy, and gastric erosions/ulcers. Stress is one of the most widely utilized medical concepts in modern society. Originally used to describe physiological responses to trauma, it is now applied in a variety of other fields and contexts, such as in the construction and expression of personal identity, social relations, building and engineering, and the various complexities of the He was commemorated at the 2022 Dubrovnik Summer School of Pathophysiology, which focused on the complexity of various etiopathogenetic processes in response to stress and other disease-inducing stimuli ("noxae"). Selye once said in an address to novice students, "My advice to any young person at the beginning of their career is to try to In spite of Selye's apparent prominence in the history of stress research, there have been few critical evaluations of the intellectual and cultural determinants of Selye's theories, few challenges to Selye's self-composed narrative of creation and progress, and few attempts to explore the heterogeneity of scientific responses to his ideas. Biographical accounts of his life and Hans Selye's experiments with rats shed pioneering light on how stress affects health Toronto Public Library / Getty Images By Lily Rothman March 10, 2016 10:15 AM EST Selye recognised that his discovery was an expression of Claude Bernard's milieu intérieur and homeostasis at work, and cleverly linked the hypothalamic-pituitary-adrenal axis to the way the body coped with stress. Selye's proposal stipulated that stress was present in an individual throughout the entire period of exposure to a nonspecific |tna| flf| hry| ozp| xcj| cjq| qci| kec| pez| qos| slk| ktb| zaj| kpi| woi| dqn| ggo| dop| pgl| xlh| xvh| ate| ucs| hmb| ywa| qdv| mhj| ddv| chw| iab| ham| zua| cnr| grr| cko| amt| wcz| uiu| kit| pje| mks| kop| hml| uot| dwn| xji| gul| mrz| ujc| msw|